Experience: Open · Type: Full-time, On-site (Bengaluru)

The Mission

Mandrake Bio is a protein-design company building the next generation of programmable gene-editing enzymes. Its platform designs editors from scratch, pairing generative AI with first-principles biophysics and wet-lab validation to engineer the compactness, precision, and dynamic control that the highest-impact applications in agriculture and medicine demand. Founded in 2025 and headquartered in Bengaluru, India. Learn more at mandrake.bio.

We are a VC-backed, small, high-velocity applied research lab. We don't care about credentials; we care about proof of work, first-principles thinking, and the ability to ship.

Don't see your exact role?

Computational biology at Mandrake spans everything from genome-scale data engineering to structure-based design. If you live at the interface of code and biology, reach out — even if our listed roles don't match exactly.

Areas we're actively growing:

• Genomics & sequencing analysis — NGS pipelines, variant calling, off-target/specificity analysis, metagenomics.
• Structural & protein bioinformatics — modeling, docking, MD, sequence-structure-function.
• Data engineering for biology — building the pipelines and infrastructure our models learn from.
• Editing analytics — quantifying editing outcomes, indels, and genomic integrity from experimental data.

Whether your interest is therapeutic or agricultural, tell us your strengths and what you'd want to own.

You're a Great Fit If You

• Are fluent in scientific Python and comfortable with large biological datasets.
• Can build reproducible, scalable analysis pipelines.
• Reason from first principles and want your analysis to drive real design decisions.

To Apply: Send your Proof of Work (code, analyses, publications) and a note on where you'd fit.

Why Mandrake

• Work on the frontier of AI × Biology — creating technologies that could redefine longevity, health, and the future of our planet.
• Join a small, high-velocity team where your ideas directly shape the company's direction and breakthroughs.